- Intestinal amoebiasis:
- Adults: 2g STAT or in 2 divided doses within 4 hours
- Children: 30mg/kg as a single dose
- Asymptomatic amoebiasis:
- 2g OD * 3/7
- Hepatic amoebiasis/ amoebic liver abscess:
- 5g OD * 5/7
- Trichomoniasis:
- 2g STAT or in 2 divided doses within 4 hours
- Giardiasis:
- Adult: 2g STAT
- Tablet:
- 1000mg
- 500mg
- Suspension:
- 750mg/30mL
- 750mg/10mL
- 1000mg/10mL
- To be taken at the beginning of a meal
5-nitroimidazole
Selective for anaerobic bacteria due to its ability to intracellularly reduce imidazole which covalently binds to DNA, disrupt its helical structure inhibiting bacterial nucleic acid synthesis.
- GI disturbances
- Epigastric pain
- Metallic taste
- Glossitis
- Stomatitis
- Urticaria
- Vertigo
- Dizziness
- Headache
- Neurological disturbances
- Alcohol
- History of blood dyscrasias
- Warfarin
- Alcohol
- Disulfiram
Drug Status
| Availability | Prescription or OTC by Pharmacist |
| Pregnancy | Contraindicated in 1st trimester |
| Breastfeeding | Contraindicated |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Agisec | 1g | Tablet | 2’s | Agio Pharma | Phillips Healthcare |
| Ambirance | 1g | Tablet | 2’s | Twokay Chemicals | Twokay Chemicals |
| C-Secni | 1g | Tablet | 2’s | Crown Healthcare | Crown Healthcare |
| Dawasec | 1g | Tablet | 2’s | Dawa Ltd | Dawa Ltd |
| Dysen | 750mg/30mL | Suspension | 1’s | Nabiqasim Industries | Harley’s Ltd |
| Dysen Forte | 1g | Tablet | 2’s | Nabiqasim Industries | Harley’s Ltd |
| Entosec | 1g | Tablet | 2’s | Cipla Ltd | Imperial Managed |
| Essnidazole | 1g | Tablet | 2’s | Essar Ltd | Essar Ltd |
| Flagentyl | 500mg | Tablet | 4’s | Sanofi-Aventis | Ressourcethica Kenya |
| Frambi | 1g | Tablet | 2’s | Crown Healthcare | Crown Healthcare |
| Labgentil | 500mg | Tablet | 4’s | Laboratory & Allied | Laboratory & Allied |
| Nidazole | 500mg | Tablet | 4’s | Curis Lifesciences | Nedah Pharma |
| Olmol Forte | 1g | Tablet | 2’s | Benmed Pharma | Benmed Pharma |
| Olmol Forte | 1g | Tablet | 2’s | Benmed Pharma | Benmed Pharma |
| Olmol Forte | 1g | Tablet | 2’s | Benmed Pharma | Benmed Pharma |
| Otisec | 1g | Tablet | 2’s | Oceanic Healthcare | Oceanic Lifecare |
| Otisec | 1g | Tablet | 2’s | Oceanic Healthcare | Oceanic Healthcare |
| Secdy | 1g | Tablet | 2’s | Shambhuprasad and Sons | Shambhuprasad and Sons |
| Secdy | 1g | Tablet | 2’s | Shambhuprasad And Sons | Zike Corporation |
| Secnagyl | 1g | Tablet | 2’s | Bliss GVS | Prunus Pharma |
| Secnefil | 1g | Tablet | 2’s | Fourrts Labs | Sai Pharma |
| Secnid | 1g/10mL | Suspension | 1’s | Square Pharma | Ace Pharma |
| Secnid DS | 1g | Tablet | 2’s | Square Pharma | Ace Pharma |
| Secnida Forte | 1g | Tablet | 4’s | Biopharma Ltd | Biopharma Ltd |
| Secnida | 750mg/15mL | Suspension | 1’s | Biopharma Ltd | Biopharma Ltd |
| Secnidazole | 1g | Tablet | 2’s | Lincoln Pharma C/O Medox Pharma | Medox Pharma |
| Secsun DS | 1g | Tablet | 2’s | Zawadi Healthcare | Zawadi Healthcare |
| Seczole-DS | 1g | Tablet | 2’s | Intas Pharma | Accord Healthcare |
| Sen-Forte | 1g | Tablet | 2’s | Metro Pharma | Metro Pharma |
| Senidol | 1g | Tablet | 2’s | Pharma Life Science | Pharma Life Science |
| Seole | 1g | Tablet | 2’s | Questa Care C/O Surgilinks Ltd | Surgilinks Ltd |
| Tagera Forte | 1g | Tablet | 2’s | Unichem Labs | Europa Healthcare |
| Unigentyl | 500mg | Tablet | 4’s | Universal Corporation | Universal Corporation |
| Vitasec Forte | 1g | Tablet | 2’s | Eastleigh Pharma | Eastleigh Pharma |
| Zonisec | 1g | Tablet | 2’s | Salama Pharma | Salama Pharma |