- Bronchitis exacerbation:
- PO 400mg BD *10/7
- Reserve for patients who have no other treatment options
- Community-acquired pneumonia:
- PO 400mg BD *10/7
- PO 400mg BD *10/7
- Skin & skin structure infections:
- PO 400mg BD *10/7
- PO 400mg BD *10/7
- Acute pelvic inflammatory disease
- PO 400mg BD *10-14 days
- PO 400mg BD *10-14 days
- Uncomplicated cystitis:
- Due to E. coli or K. pneumoniae: PO 200mg BD *3/7
- Due to other approved pathogens: PO 200mg BD *1/52
- Complicated UTI:
- PO 200mg BD *10/7
- Typhoid fever (Off-label):
- PO 400mg BD *7-14 days
Tablet: 200mg; 400mg
- Do not take with antacids or dairy products
Flouroquinolone
It inhibits bacterial DNA gyrase, which in turn inhibits DNA replication, transcription and repair, causing bacterial cell death.
- Nausea
- Diarrhea
- Vomiting
- Abnormal ECG
- Headache
- Dyspepsia
- Dizziness
- Restlessness
- Lightheadedness
- Vaginitis
- Insomnia
- Photosensitivity
- Pruritus
- Rash
- Anxiety
- Agitation
- Confusion
- Tendinitis
- Arthralgia
- Elevated LFTs
- Myalgia
- Disorientation
- Attention disturbance
- Nervousness
- Impaired memory
- Delirium
- Paranoia
- Hallucinations
- Nightmares
- Tremor
- Hyperglycemia
- Hypersensitivity to components
- Patients >60 years
- Myasthenia gravis
- QT prolongation
- Uncorrected electrolyte abnormalities
- Aortic aneurysm history or risk
- Marfan syndrome
- Ehlers-Danlos syndrome
- Breastfeeding during treatment and for 2 days after discontinuation
- Pimozide
- Thioridazine
Drug Status
| Availability | Prescription or OTC by Pharmacist |
| Pregnancy | Category C |
| Breastfeeding | Contraindicated |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Ofla-OD | 400mg | Tablet | 10’s | PSM Pharma | PSM Pharma |
| Oflomac | 200mg | Tablet | 60’s | Macleods Pharma | Sai Pharma |
| Ojen | 400mg | Tablet | 10’s | Jenburkt Pharma | Unisel Ltd |
| Sunflox | 400mg | Tablet | 10’s | Zawadi Healthcare | Zawadi Healthcare |
| Toflox | 200mg | Tablet | 100’s | Lincoln Pharma | Medox Pharma |