Infections by beta-lactamase producing staphylococci.
- Skin & soft tissue infections e.g. boils, carbuncles, cellulitis, infected wounds, infected burns, impetigo.
- Infected skin conditions: ulcer, eczema, acne
- RTI: pneumonia, lung abscess, sinusitis, pharyngitis, tonsillitis, otitis media, emphysema
Oral
- Adult: 250-500mg QID
- 2-10 years: 125-250mg QID
- <2 years: 62.5mg-125mg QID
IM:
- Adult: 250mg-500mg QID
Slow IV injection/infusion:
- Adult: 0.25g-2g QID
- 2-10 years: 0.125g-1g QID
- <2 years: 62.5mg-500mg QID
Capsule:
- 250mg
- 500mg
Suspension:
- 125mg/5mL
Injection:
- 500mg/vial
- To be taken 1 hour before meals
Isoxazolyl penicillin.
It inhibits synthesis of bacterial cell wall hence bactericidal.
- Hypersensitivity reactions such as urticaria and purpura
- Pseudomembranous colitis
- Hepatitis
- Cholestatic jaundice
- Interstitial nephritis
- Neutropenia
- Thrombocytopenia
- Hypersensitivity to class/compound
- Aminoglycosides
- Probenecid (prolong effects of flucloxacillin)
Drug Status
| Availability | Prescription or OTC by Pharmacist |
| Pregnancy | Category B1; Use with caution |
| Breastfeeding | Use with caution |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Dawaflox | 125mg/5mL | Suspension | 100mL | Dawa Ltd | Dawa Ltd |
| Dawaflox | 250mg | Capsule | 100’s | Dawa Ltd | Dawa Ltd |
| Dawaflox | 500mg | Capsule | 100’s | Dawa Ltd | Dawa Ltd |
| Elyflox | 250mg | Capsule | 100’s | Elys Chemicals | Elys Chemicals |
| Elyflox | 125mg/5mL | Suspension | 100mL | Elys Chemicals | Elys Chemicals |
| Floxamed | 500mg | Injection | 10’s | Pro Med Pharma | Pro Med Pharma |
| Floxapen | 500mg | Capsule | 100’s | GSK Ltd | GSK Ltd |
| Floxapen | 500mg | Injection | 10’s | GSK Ltd | GSK Ltd |
| Floxapen | 250mg | Injection | 10’s | GSK Ltd | GSK Ltd |
| Floxapen | 250mg | Capsule | 100’s | GSK Ltd | GSK Ltd |
| Floxapen | 125mg/5mL | Suspension | 100mL | GSK Ltd | GSK Ltd |
| Floxazed | 500mg | Injection | 1’s | Zawadi Healthcare | Zawadi Healthcare |
| Flucillin | 250mg | Tablet | 100’s | Synermed Pharma | Synermed Pharma |
| Flucillin | 500mg | Tablet | 100’s | Synermed Pharma | Synermed Pharma |
| Fluclox | 500mg | Injection | 1’s | Advanced Chemical | Radiance Pharma |
| Flucloxacillin | 250mg | Capsule | 100’s | Cosmos Ltd | Cosmos Ltd |
| Flucloxacillin | 500mg | Capsule | 100’s | Crown Healthcare | Crown Healthcare |
| Flucloxacillin | 500mg | Injection | 1’s | Shandong Xier Kangtai | Shandong Xier Kangtai |
| Flucloxin | 250mg | Capsule | 30’s | Eskayef Ltd | Umoja Pharma |
| Flucloxin | 500mg | Capsule | 30’s | Eskayef Ltd | Umoja Pharma |
| Flupen | 250mg | Capsule | 100’s | Kopran Ltd | Surgilinks Ltd |
| Flupene | 500mg | Injection | 1’s | Crown Healthcare | Crown Healthcare |
| Flux | 250mg | Capsule | 28’s | Opsonin Pharma | Radiance Pharma |
| Flux | 500mg | Injection | 50’s | Opsonin Pharma | Opsonin Pharma |
| Flux | 500mg | Capsule | 28’s | Opsonin Pharma | Radiance Pharma |
| Flux DS | 250mg/5mL | Suspension | 100mL | Radiance Pharma | Radiance Pharma |
| Kloxy-F | 500mg | Capsule | 100’s | Laboratory & Allied | Laboratory & Allied |
| Kloxy-F | 250mg | Capsule | 100’s | Laboratory & Allied | Laboratory & Allied |
| Kloxy-F | 500mg | Injection | 100mL | Laboratory & Allied | Laboratory & Allied |
| Phylopen | 125mg/5mL | Suspension | 100mL | Square Pharma | Ace Pharma |
| Phylopen DS | 500mg | Capsule | 20’s | Square Pharma | Ace Pharma |
| Rivaflux | 500mg | Capsule | 20’s | Riva Pharma | Salama Pharma |
| Vabiotic | 500mg | Capsule | 100’s | Eastleigh Pharma | Eastleigh Pharma |