- Complicated intra-abdominal infections:
- IM/IV 1g OD *5-14 days
- 3 months-12 years: 30mg/kg/day divided BD*5-14 days
- Complicated bacterial skin & skin structure infections:
- IM/IV 1g OD *7-14 days
- Including diabetic foot infections without osteomyelitis
- 3 months-12 years: 30mg/kg/day divided BD*7-14 days
- Community-acquired pneumonia:
- Adults & >13 years: IM/IV 1g OD *5/7
- 3 months-12 years: 30mg/kg/day divided BD*10-14 days
- Complicated UTI:
- Adults & >13 years: IM/IV 1g OD *10-14 days
- 3 months-12 years: 30mg/kg/day divided BD*10-14 days
- Gynecological infections:
- Adults & >13 years: IM/IV OD *3-10 days
- 3 months-12 years: 30mg/kg/day divided BD*3-10 days
- Colorectal surgery infection prophylaxis:
- Adults: IV 1g *1
- >1 year old: 15 mg/kg/dose IV x1
- Given 60 min prior
Injection: 1g
- Infused over 30 minutes
- Reconstituted IV solution may be either stored at room temperature and used within 6 hours or refrigerated, stored for up to 24 hours, and used within 4 hours after removal from refrigerator
Carbapenem
It binds to peptidoglycan thereby inhibiting cell wall synthesis. Resistant to most beta lactamases
- Diarrhea
- Infusion site reaction
- Nausea
- Vomiting
- Increased ALT/AST
- Increases alkaline phosphate
- Headache
- Fever
- Altered mental status
- Constipation
- Abdominal pain
- Edema
- Insomnia
- Thrombocytosis
- Dyspnea
- Rash
- Hypersensitivity to class/components
- Hypersensitivity to amide anesthetics (IM use)
None restricted
Drug Status
| Availability | Prescription only |
| Pregnancy | Category B |
| Breastfeeding | Can be used |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Invanz | 1g | Injection | 1’s | MSD Ltd | Imperial Managed |