• Respiratory tract infections
  • Otitis media
  • Skin & soft tissue infections
  • Bone & joint infections
  • Genito-urinary infections
    • Adult: 250mg QID OR 500mg TDS [increased to 1-1.5g TDS for severe infections]
    • Children: 25mg/kg in divided doses [can be doubled for severe infections]
    • 6-12 years: 250mg BD
    • 1-5 years: 125mg TDS
    • Under 1 year: 125mg BD

Capsules:

  • 250mg
  • 500mg

Suspension:

  • 125mg/5mL
  • 250mg/5mL

Injection:

  • 18% w/v
  • Can be taken with/without food.

1st  generation cephalosporin.

Binds to penicillin binding proteins, which in turn inhibit synthesis of bacterial cell wall hence bactericidal.

  • Diarrhea
  • Nausea
  • Vomiting
  • Dyspepsia
  • Gastritis
  • Abdominal pain
  • Hypersensitivity to cephalosporins or penicillins.
  • Probenecid delays excretion.
  • Increased nephrotoxicity with amphotericin, loop diuretics, aminoglycosides, capreomycin or vancomycin

                                   Drug Status

Availability Prescription or OTC by Pharmacist
Pregnancy Category A
Breastfeeding Can be used
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
C-Lex 500mg Capsule 100’s Zawadi Healthcare Zawadi Healthcare
C-Lex DS 125mg/5mL Suspension 100mL Zawadi Healthcare Zawadi Healthcare
Cefacure 500mg Capsule 100’s Orchid Healthcare Europa Healthcare
Cefacure 250mg Capsule 100’s Orchid Healthcare Europa Healthcare
Cefalin 500mg Capsule 50’s Harley’s Ltd Harley’s Ltd
Cefamor 500mg Capsule 100’s Cadila Pharma Cadila Pharma
Cefamor 125mg/5mL Suspension 100mL Cadila Pharma Cadila Pharma
Cefamor 125mg/5mL Suspension 100’s Cadila Pharm Cadila Pharm
Cefamor 250mg Capsule 100’s Cadila Pharm Cadila Pharm
Cefax 250mg Capsule 100’s Sakar Healthcare Harley’s Ltd
Cefax 500mg Capsule 10’s Sakar Healthcare Harley’s Ltd
Cephast 500mg Capsule 100’s Sterling Labs Pharma Specialities
Cephastal 500mg Capsule 100’s Medox Pharma Medox Pharma
Cephastal 250mg Capsule 100’s Medox Pharma Medox Pharma
Cephastal 125mg/5mL Suspension 100mL Medox Pharma Medox Pharma
Corfex 250mg Capsule 100’s Unosource Pharma Unisel Ltd
Corfex 500mg Capsule 100’s Unosource Pharma Unisel Ltd
Felaxin 125mg/5mL Suspension 100mL Crown Healthcare Crown Healthcare
Leocef 500mg Capsule 100’s Laboratory & Allied Laboratory & Allied
Leocef 125mg/5mL Suspension 100mL Laboratory & Allied Laboratory & Allied
Lexin 125mg/5mL Capsule 10’s Harley’s Ltd Harley’s Ltd
Medalexin 500mg Tablet 100’s Medisel Kenya Medisel Kenya
Mediceff 125mg/5mL Suspension 100mL; 60mL Medivet Products Medivet Products
Oracef 250mg Capsule 100’s Dawa Ltd Dawa Ltd
Oracef 500mg Capsule 100’s Dawa Ltd Dawa Ltd
Oracef 125mg/5mL Capsule 100mL Dawa Ltd Dawa Ltd
Ospexin 500mg Tablet 12’s Sandoz GMBH Sandoz GMBH
Rivalexin 125mg/5mL Suspension 100mL Riva Pharma Salama Pharma
Rivalexin 250mg/5mL Suspension 100mL Riva Pharma Salama Pharma
Rivalexin 500mg Capsule 100’s Riva Pharma Salama Pharma