- Pneumonia:
- Complicated: IV 2g TDS *7/7
- Uncomplicated: IV 0.5-1g TDS *7/7
- Bone & joint infections:
- IV 2g BD
- Gynecologic & intra-abdominal Infections:
- IV 2g TDS * 4-7 days
- Meningitis:
- IV 2g TDS
- Urinary Tract Infections:
- Complicated: IV/IM 500mg BD/TDS
- Uncomplicated: IV/IM 250mg BD
- Life-threatening infections, esp. immuno-compromised patients
- IV 2g TDS
Up to 2 months: IV 25-60mg/kg/day in 2 divided doses.
Children:
- 1 month-12 years: IV 30-150 mg/kg IV q8hr.
- Max 6g/day (higher end of dosing range reserved for patients who are immune-compromised and/or with meningitis or cystic fibrosis)
Injection:
- 1g
- 2g
- IV direct injection: Inject over 3-5 minutes directly into vein or through tubing of running compatible infusion solution.
- Infusion: Infuse intermittently over 15-30 minutes.
- IM: deep tissue
3rd generation cephalosporin.
Bactericidal. It inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins thereby inhibiting the final transpeptidation step of peptidoglycan synthesis.
- Injection site pain
- Eosinophilia
- Diarrhoea
- Hypersensitivity reactions
- Rash
- Thrombocytosis
- Fever
- CNS effects
- Hypersensitivity to beta lactams
- Live attenuated vaccines
- Bumetanide
Drug Status
| Availability | Prescription only |
| Pregnancy | Category B; Safe to use |
| Breastfeeding | Safe to use |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Auromitaz | 1g | Injection | 1’s | Aurobindo Pharma | Simba Pharma |
| C-Zid | 1g | Injection | 1’s | Emcure Pharma | Lazor Pharma |
| Ceztazid | 1g | Injection | 1’s | Medox Pharma | Medox Pharma |
| Fortum | 1g | Injection | 1’s | GSK Ltd | GSK Ltd |
| Fortum | 2g | Injection | 1’s | GSK Ltd | GSK Ltd |
| Keftaz | 1g | Injection | 1’s | Galpha Labs | Medilife Biologicals |
| Syner-zed | 1g | Injection | 1’s | Synermed Pharma | Synermed Pharma |
| Tazid | 1g | Injection | 1’s | Square Pharma | Ace Pharma |
| Tazid | 250mg | Injection | 1’s | Square Pharma | Ace Pharma |
| Xtrazid | 1g | Injection | 1’s | Nabiqasim Industries | Harley’s Ltd |
| Zidimbiotic | 1g | Injection | 1’s | Beta Healthcare | Zuvan Limited |