- Pharyngitis/ tonsillitis:
- Adults: PO 1g OD or divided BD *10/7
- Children: PO 30 mg/kg/day divided BD*10/7
- Uncomplicated UTI:
- PO 1-2g OD or divided BD *3-7 days
- Not 1st line
- Skin & soft tissue infections:
- Adults: PO 1g OD or divided BD *5-7 days
- Children: PO 30mg/kg/day divided BD *5-7 days
- Prophylaxis of endocarditis (dental, upper respiratory procedure):
- PO 2g 1 hour before procedure
Capsule:
- 500mg
- 1g
Suspension:
- 125mg/5mL
- 250mg/5mL
Taken without regard to food
1st generation cephalosporin
It binds to peptidoglycan inhibiting cell wall synthesis thereby inhibiting bacterial growth
- Diarrhea
- Nausea
- Dyspepsia
- Urticaria
- Pruritus
- Rash
- Vomiting
- Elevated ALT/AST
- Hypersensitivity to class/components
- BCG live vaccine
Drug Status
| Availability | Prescription only |
| Pregnancy | Can be used |
| Breastfeeding | Can be used |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Actidrox | 1g | Tablet | 10’s | Krishna Chemists | Krishna Chemists |
| Actidrox | 500mg | Capsule | 14’s | Krishna Chemists | Krishna Chemists |
| Actidrox | 250mg/5mL | Suspension | 60mL | Krishna Chemists | Krishna Chemists |
| Adora | 125mg/5mL | Suspension | 60mL, 100mL | Incepta Pharma | Radiance Pharma |
| Alcephine | 500mg | Capsule | 100’s | Pharmamed Solution | Topstone Pharma |
| Biodroxil | 125mg/5mL | Suspension | 60mL | Sandoz GMBH | Novartis Kenya |
| Biodroxil | 250mg/5mL | Suspension | 60mL, 100mL | Sandoz GMBH | Novartis Kenya |
| Biodroxil | 1g | Tablet | 12’s | Sandoz GMBH | Novartis Kenya |
| Biodroxil | 500mg | Capsule | 12’s | Sandoz GMBH | Novartis Kenya |
| C-Drox | 500mg | Capsule | 10’s | Zawadi Healthcare | Zawadi Healthcare |
| C-Drox DS | 125mg/5mL | Suspension | 60mL, 100mL | Zawadi Healthcare | Zawadi Healthcare |
| Cedril | 500mg | Tablet | 100’s | Medox Pharma | Medox Pharma |
| Cedril DS | 250mg/5mL | Suspension | 100mL | Medox Pharma | Medox Pharma |
| Cexil | 125mg/5mL | Suspension | 100mL | Leben Labs | Unisel Ltd |
| Cexil | 250mg/5mL | Suspension | 100mL | Leben Labs | Unisel Ltd |
| Cexil | 500mg | Tablet | 10’s | Leben Labs | Unisel Ltd |
| Cordoxyl | 500mg | Tablet | 10’s | Signature Healthcare | Signature Healthcare |
| Dawadroxyl | 500mg | Tablet | 10’s | Dawa Ltd | Dawa Ltd |
| Dawadroxyl | 125mg/5mL | Suspension | 100mL | Dawa Ltd | Dawa Ltd |
| Drox | 250mg | Suspension | 100mL | Aurobindo Pharma | Simba Pharma |
| Drox | 500mg | Capsule | 100’s | Aurobindo Pharma | Simba Pharma |
| Duraxyl | 500mg | Capsule | 20’s | Laboratory & Allied | Laboratory & Allied |
| Flamicef | 500mg | Capsule | 20’s | Harley’s Ltd | Harley’s Ltd |
| Mydrox | 500mg | Capsule | 20’s | National Pharmacy | National Pharmacy |
| Trydrox | 500mg | Tablet | 10’s | Twenty First Century | Twenty First Century |
| Vedrox | 125mg/5mL | Suspension | 60mL, 100mL | Indoco Remedies | Sai Pharma |
| Vedrox | 500mg | Capsule | 20’s | Indoco Remedies | Sai Pharma |