- Group A Streptococcal upper respiratory infections e.g. pharyngitis, tonsillitis:
- Adults: 2 million units IM *1
- Older children: 900,000 units *1
- Infants and younger children: 300,000-600,000 units *1
- Syphilis; primary, secondary or latent <1 year:
- 4 million units IM *1; may repeat dose after 1 week for pregnant patients
- Syphilis; tertiary, latent >1 year or unknown duration:
- 4 million units IM per week *3/52
- Rheumatic fever prophylaxis:
- 2 million units every 4 weeks or 600,000 units every 2 weeks
Injection:
- 2.4 MU
- NOT to be used IV.
- Should NOT be mixed with other IV solutions.
- Do NOT inject near nerve or artery.
- Deep IM use
- Administered only in the upper or outer quadrant of dorsogluteal or ventrogluteal site
Penicillin antibiotic.
It inhibits cell wall mucopeptide synthesis especially during active multiplication hence bactericidal.
- Rash
- Urticaria
- Pseudomembranous colitis
- Serum-sickness like reaction (fever, chills, edema, arthralgia, prostration)
- Jarisch-Herxheimer reaction
- Hypersensitivity reactions
- IV administration
- BCG live vaccine
- Probenecid- prolongs half-life of Pen G. May be used for this purpose.
Drug Status
Availability | Prescription only |
Pregnancy | Category B; Can be used |
Breastfeeding | Safe to use |
Schedule | Not controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Benzapene 2.4 | 2.4 MU | Injection | 1’s | Crown Healthcare | Crown Healthcare |
Benzathine Penicillin | 2.4 MU | Injection | 1’s | Ray Pharma | Ray Pharma |
Carebenzar | 2.4 MU | Injection | 1’s | Careplus Ltd | Careplus Ltd |
Medur | 2.4 MU | Injection | 1’s | Medisel Kenya | Medisel Kenya |