• UTI:
    • 500mg TDS 
  • Bronchitis:
    • Uncomplicated: 250mg QID
    • Severe: 1g QID
  • Gonorrhea:
    • 2 g PO with 1 g probenecid as a single dose.
    • Repeated doses are recommended for the treatment of females.
  • Community-acquired pneumonia:
    • 500mg QID 
  • ENT infections:
    • 250mg QID 
  • Septicaemia:
    • Adult: 250mg-1g every 6 hours
    • Children <10years: half adult dose
  • Endocarditis (in combination with an aminoglycoside/other antibiotic):
    • IV 2g every 4-6 hours 
  • Listeria meningitis (in combination with an aminoglycoside/other antibiotic):
    • Adult: 2g every 4 hours *10-14 days
    • Neonate: 50mg/kg every 6 hours
    • 1-3 months: 50-100mg/kg every 6 hours
    • 3 months-12 years: 100mg/kg every 6 hours
  • GIT infections:
    • 500-750 mg TDS/QID 
  • Enteric fever:
    • Acute: 1-2 g QID *2/52
    • Carriers: 1-2 g QID * 4-12 weeks

Capsule: 250mg, 500mg

Suspension: 125mg/5ml

Injection: 250mg

For oral route, best taken 30 min before meals.

Broad-spectrum penicillin.

It inhibits cell wall mucopeptide synthesis thereby causing cell death. Bactericidal

Ampicillin has generally been replaced by amoxicillin for the treatment of many infections due to more reliable absorption and bioavailability.

  • Nausea
  • Vomiting
  • Diarrhoea
  • Hypersensitivity reaction
  • Eosinophilia
  • Glossitis
  • Black hairy tongue
  • Oral/Vulvovaginal candidiasis
  • Increase in transaminases
  • Hypersensitivity to beta lactam antibiotics
  • Mononucleosis
  • Tetracyclines
  • BCG vaccine
  • Typhoid vaccine

                                   Drug Status

Availability Prescription or OTC by Pharmacist
Pregnancy Category B; Can be used
Breastfeeding Use with caution; possible risk of thrush
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Ampecin 125mg/5mL Suspension 60mL, 100mL Dawa Ltd Dawa Ltd
Ampicillin 500mg Injection 1’s Crown Healthcare Crown Healthcare
Ampicillin 500mg Capsule 100’s Crown Healthcare Crown Healthcare
Ampicillin 500mg Injection 1’s Laboratory & Allied Laboratory & Allied
Lacillin 500mg Capsule 100’s Laboratory & Allied Laboratory & Allied
Lacillin 250mg Capsule 100’s Laboratory & Allied Laboratory & Allied
Lacillin 125mg/5mL Suspension 60mL, 100mL Laboratory & Allied Laboratory & Allied
Pcillin 250mg Capsule 100’s Zest Pharma Synermed Pharma
Pcillin 500mg Capsule 100’s Zest Pharma Synermed Pharma