- Heavy menstrual bleeding associated with pain:
- PO 1 tab TDS *5/7
Mefenamic Acid:
- 250mg
- 500 mg
Tranexamic Acid:
- 500mg
- Take with food to reduce gastrointestinal discomfort.
- Do not exceed the recommended dose and avoid use for more than 5 days.
Mefenamic Acid (NSAID): Inhibits COX-1 and COX-2, reducing prostaglandin production, thereby relieving pain and reducing inflammation and menstrual bleeding.
Tranexamic Acid (Antifibrinolytic): Inhibits plasminogen activation, preventing excessive breakdown of blood clots, which reduces heavy bleeding.
- Nausea
- Vomiting
- Diarrhea
- Stomach pain
- Dizziness
- Risk of GI bleeding with prolonged use
- Active GI bleeding or ulcers
- History of thromboembolic events
- Severe renal or hepatic impairment
- Anticoagulants
- Diuretics
- Antihypertensives
- Oral contraceptives
- Hormone replacement therapy (HRT)
Drug Status
| Availability | Prescription only |
| Pregnancy | Contraindicated in late pregnancy due to the risk of premature closure of the ductus arteriosus |
| Breastfeeding | Use with caution |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Amica | 250mg/500mg | Tablet | 20’s | PSM Pharma | PSM Pharma |
| Mefcid TA | 250mg/500mg | Tablet | 10’s | Zest Pharma | Synermed Pharma |
| Tramed | 250mg/500mg | Tablet | 30’s | Comed Chemicals Ltd | Ripple Pharma |
| TX-MF | 250mg/500mg | Tablet | 30’s | Ochoa Labs | Dawa Ltd |