- Osteoarthritis, chronic musculoskeletal disorders & dysmenorrhea:
- 60mg OD
- Rheumatoid arthritis, ankylosing spondylitis:
- 90mg OD
- Pain following dental surgery & acute gout:
- 120mg OD
Tablet:
- 60mg
- 90mg
- 120mg
- Not suitable for children <16 years.
- To be taken after meals.
- Monitor blood pressure regularly.
NSAID. Selective COX-2 inhibitor.
COX-2 has been shown to be primarily responsible for the synthesis of prostanoid mediators of pain, inflammation and fever.
- Dry mouth
- Taste disturbance
- Oedema
- Dizziness
- Headache
- Palpitations
- Increased BP
- GI disorders
- Diarrhoea
- Dyspepsia
- Epigastric discomfort
- Increased ALT and AST
- Ecchymosis
- Fatigue
- Flu-like symptoms
- Hypersensitivity to components
- Active peptic ulceration or GI bleeding
- Severe hepatic impairment
- CrCl <30ml/min
- Children < 16 years
- Inflammatory bowel disease
- CHF
- Patients with signs of asthma, acute rhinitis, nasal polyps, angioneurotic oedema or urticaria
- Pregnancy & lactation
- Oral anticoagulants
- Diuretics
- ACE inhibitors
- Aspirin
- Oral contraceptives
- Rifampicin
Drug Status
| Availability | Prescription or OTC |
| Pregnancy | Category X; Contraindicated |
| Breastfeeding | Contraindicated |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Arcoxia | 90mg | Tablet | 7’s; 28’s | MSD Ltd | Imperial Managed |
| Arcoxia | 60mg | Tablet | 28’s | MSD Ltd | Imperial Managed |
| Arcoxia | 120mg | Tablet | 7’s; 28’s | MSD Ltd | Imperial Managed |
| Cox E | 30mg | Tablet | 30’s | Zest Pharma | Synermed Pharma |
| Cox E | 90mg | Tablet | 30’s | Zest Pharma | Synermed Pharma |
| Coxirav | 120mg | Tablet | 10’s | Ravian Life Sciences | Pharma Branding Ltd |
| Doloxia | 120mg | Tablet | 10’s | Dolopharma Healthcare | Dolopharma Healthcare |
| Doloxia | 90mg | Tablet | 10’s | Dolopharma Healthcare | Dolopharma Healthcare |
| Ecocib | 90mg | Tablet | 10’s | Dawa Ltd | Dawa Ltd |
| Ecofree | 90mg | Tablet | 10’s | Medisel Kenya | Medisel Kenya |
| Ecofree | 120mg | Tablet | 10’s | Medisel Kenya | Medisel Kenya |
| Etcox | 90mg | Tablet | 30’s | Laso Healthcare | Simba Pharma |
| Etcox | 120mg | Tablet | 30’s | Laso Healthcare | Simba Pharma |
| Etorix | 90mg | Tablet | 30’s | Eskayef Ltd | Umoja Pharma |
| Etorix | 60mg | Tablet | 40’s | Eskayef Ltd | Umoja Pharma |
| Etorix | 120mg | Tablet | 20’s | Eskayef Ltd | Umoja Pharma |
| ETR | 90mg | Tablet | 30’s | Zawadi Healthcare | Zawadi Healthcare |
| ETR | 60mg | Tablet | 30’s | Zawadi Healthcare | Zawadi Healthcare |
| ETR | 120mg | Tablet | 30’s | Zawadi Healthcare | Zawadi Healthcare |
| Etoflam | 60mg | Tablet | 10’s | Krishna Chemists | Krishna Chemists |
| Etoflam | 90mg | Tablet | 10’s | Krishna Chemists | Krishna Chemists |
| Etoflam | 120mg | Tablet | 10’s | Krishna Chemists | Krishna Chemists |
| Etrib | 60mg | Tablet | 30’s | Nirpo JMI Pharma | Avacare Kenya |
| Etrib | 90mg | Tablet | 30’s | Nirpo JMI Pharma | Avacare Kenya |
| Newcox | 60mg | Tablet | 30’s | Pharma Life Science | Pharma Life Science |
| Newcox | 90mg | Tablet | 30’s | Pharma Life Science | Pharma Life Science |
| Newcox | 120mg | Tablet | 30’s | Pharma Life Science | Pharma Life Science |
| Nucoxia | 60mg | Tablet | 30’s | Cadila Pharma | Cadila Pharma |
| Nucoxia | 90mg | Tablet | 30’s | Cadila Pharma | Cadila Pharma |
| Nucoxia | 120mg | Tablet | 30’s | Cadila Pharma | Cadila Pharma |
| Oricox | 90mg | Tablet | 30’s | Nextgen Pharma | Nextgen Pharma |
| Tory | 120mg | Tablet | 20’s | Square Pharma | Ace Pharma |
| Tory | 60mg | Tablet | 20’s | Square Pharma | Ace Pharma |
| Tory | 90mg | Tablet | 20’s | Square Pharma | Ace Pharma |
| Veroxib | 120mg | Tablet | 30’s | Unosource Pharma | Unisel Ltd |
| Veroxib | 90mg | Tablet | 30’s | Unosource Pharma | Unisel Ltd |
| Veroxib | 60mg | Tablet | 30’s | Unosource Pharma | Unisel Ltd |
| Xibra | 60mg | Tablet | 10’s | Tiba Healthcare | Wessex Pharma |
| Xibra | 90mg | Tablet | 10’s | Tiba Healthcare | Wessex Pharma |
| Xibra | 120mg | Tablet | 10’s | Tiba Healthcare | Wessex Pharma |