- GERD
- Zollinger-Ellison syndrome
- Peptic ulcers
Dose: 1 cap OD
- Tablet/capsule:
- 40mg/30mg
- To be taken 30 min before meals
Esomeprazole: Proton pump inhibitor. It suppresses gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells. It inhibits the proton pump, the final step in gastric acid secretion
Domperidone: Dopamine antagonist. It works as an upper GI prokinetic and increases the tone of the lower esophageal sphincter and enhances gastric emptying
- Dry mouth
- Stomach pain
- Diarrhoea
- Headache
- Flatulence
- Clostridium difficile-associated diarrhoea (CDAD)
- Bone fractures
- Hyperprolactinemia
- Prolactinoma
- blockage in the intestines
- GI bleeding
- Moderate to severe liver disease
- Atazanavir
- Saquinavir
- Ritonavir
- Nelfinavir
- Warfarin
- Clopidogrel
- Ketoconazole
- Itraconazole
- Voriconazole
- Fluconazole
- Erlotinib
- Toremifene
- Vandetanib
- Vincamine
- Diazepam
- Phenytoin
- Cilostazol
- Cisapride
- Dolasetron
- Tacrolimus
- Rifampicin
- Erythromycin
- Clarithromycin
- Moxifloxacin
- Pentamidine
- Telithromycin
- Levothyroxine
- Methotrexate
- Citalopram
- Escitalopram
- Digoxin
- Halofantrine
- Haloperidol
- Pimozide
- Sertindole
- Mequitazine
- Mizolastine
- Amiodarone
- Dronedarone
- Quinidine
- Disopyramide
- Dofetilide
- Sotalol
- Diltiazem
- Veramapil
Drug Status
| Availability | Prescription or OTC |
| Pregnancy | Weigh risk vs benefit |
| Breastfeeding | Weigh risk vs benefit |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Esofag D | 40mg/30mg | Capsule | 30’s | Micro Labs | Micro Labs |
| Epraz | 40mg | Capsule | 30’s | PSM Pharma | PSM Pharma |