- General anesthesia induction:
- Slow IV 1-4.5mg/kg *1 OR 5-2mg/kg if adjuvant drugs used e.g. midazolam
- OR
- IM 6.5-13mg/kg *1 OR 4-10 mg/kg if adjuvant drugs used e.g. midazolam
- General anesthesia maintenance:
- 1-0.5mg/min IV continuous infusion OR
- IV 0.5-4.5mg/kg/dose PRN OR
- IM 3.25-13mg/kg/dose PRN
- Moderate-severe acute pain (Off-label):
- IV 0.1-0.35mg/kg/dose *1 OR 0.1-1 mg/kg/h PRN
- IV 0.1-0.35mg/kg/dose *1 OR 0.1-1 mg/kg/h PRN
- Moderate-severe chronic pain (Off-label):
- IV 0.5-2mg/kg/h OR 1-0.35mg/kg/dose *1
Injection: 50mg/mL
Do not give 100 mg/mL preparation undiluted
General anesthetic
It antagonizes N-methyl-D-aspart (NMDA) receptors in the CNS, producing dissociative analgesia and sedation
- Sialorrhea
- Anorexia
- Nausea
- Vomiting
- Elevated BP
- Elevated HR
- Diplopia
- Nystagmus
- Lacrimation
- Fasciculations
- Depressed reflexes
- Emergence delirium
- Bradycardia
- Hypotension
- Cystitis
- Hypersensitivity to components
- Hypertension
- Stroke
- Intracranial mass
- Intracranial hemorrhage
- Isocarboxazid
- Phenelzine
- Tranylcypromine
Drug Status
Availability | Prescription only |
Pregnancy | Not recommended |
Breastfeeding | Unknown; weigh risk vs benefit |
Schedule | Controlled |
BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
---|---|---|---|---|---|
Brevinaze | 50mg/mL | Injection | 10mL | Pharmax India | Reddys Pharma |
Ketajex | 50mg/mL | Injection | 10mL | Elda International | Reddys Pharma |
Ketamax | 50mg/mL | Injection | 10mL | Troikaa | Harley’s Ltd |
Ketamine | 50mg/mL | Injection | 10mL | Umedica Labs | Unisel Ltd |
Ketamine | 50mg/mL | Injection | 10mL | Rotexmedica GmbH | Nairobi Pharma |
Ketamine | 50mg/mL | Injection | 10mL | Dawa Ltd | Dawa Ltd |
Ketamine Fresenius | 500mg/10mL | Injection | 10’s | Fresenius Kabi | Surgipharm Ltd |
Ketanir | 50mg/mL | Injection | 10mL | Aculife Healthcare | Unisel Ltd |
Ketavit | 50mg/mL | Injection | 10mL | Reddys Pharma | Reddys Pharma |
Pentyl | 50mg/mL | Injection | 10mL | Advanced Chemical Industries | Radiance Pharma |
Verket | 50mg/mL | Injection | 10mL | M/S Verve Human Care | Generics Africa |