• Allergic rhinitis (seasonal or perennial) with nasal congestion
  • Sinusitis with allergy symptoms
  • Common cold-related congestion and allergy symptoms

Dosage (Adults & Children 12+):

  • Desloratadine 5 mg + Pseudoephedrine 120 mg: Usually taken twice daily (every 12 hours)
  • or
  • Desloratadine 5 mg + Pseudoephedrine 240 mg: Once daily (extended-release)

Children (6–11 years):

  • Not typically recommended without pediatric-specific formulation or doctor supervision.
  • Desloratadine 5 mg + Pseudoephedrine 120 mg (12-hour formulation)
  • Desloratadine 5 mg + Pseudoephedrine 240 mg (24-hour extended-release)
  • Take with or without food.
  • Swallow whole (especially ER tablets); do not crush or chew.
  • Take early in the day to avoid insomnia (due to pseudoephedrine).
  • Avoid caffeine and other stimulants.

Desloratadine:

  • A long-acting, non-sedating H1-antihistamine.
  • Reduces allergy symptoms like sneezing, itching, and runny nose.

Pseudoephedrine:

  • A sympathomimetic (decongestant).
  • Acts on alpha-adrenergic receptors causing vasoconstriction in nasal passages, reducing congestion.

Desloratadine:

  • Headache
  • Fatigue
  • Dry mouth
  • Drowsiness (rare)

Pseudoephedrine:

  • Insomnia
  • Nervousness
  • Increased heart rate (tachycardia)
  • Increased blood pressure
  • Dizziness
  • Hypersensitivity to either component
  • Severe hypertension or coronary artery disease
  • MAO inhibitor use within the last 14 days
  • Narrow-angle glaucoma
  • Urinary retention
  • Hyperthyroidism
  • MAO inhibitors: Risk of hypertensive crisis with pseudoephedrine
  • Beta-blockers: May reduce antihypertensive effect
  • CNS stimulants or alcohol: Additive CNS effects
  • Other decongestants or antihistamines: Increased risk of side effects

                                   Drug Status

Availability
Pregnancy
Breastfeeding
Schedule
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Aerinaze MR 2.5mg/120mg Tablet 14’s MSD Ltd Imperial Managed