• GERD:
    • Symptomatic non-erosive: PO 15mg OD *8/52
    • Short-term treatment in erosive esophagitis:
      • Adults: PO 30mg OD *8-16 weeks
      • <30 kg: PO 15mg OD for *8-12 weeks
      • >30 kg: PO 15mg OD for *8-12 weeks
    • Maintenance treatment in erosive esophagitis: PO 15mg OD
  • Duodenal ulcer:
    • PO 15mg OD *4/52. Maintenance: 15mg OD
  • Gastric ulcer:
    • PO 30mg OD *8/52
  • NSAID-associated gastric ulcer:
    • Treatment: PO 30mg OD *8/52
  • Hypersecretory conditions:
    • Initially PO 60mg OD
    • Up to 180mg BD can be used
  • H.pylori infection:
    • Triple therapy: Lansoprazole 30mg + amoxicillin 1g + clarithromycin 500mg BD *10-14 days
    • Dual therapy (clarithromycin resistant): Lansoprazole 30mg + amoxicillin 1g TDS *2/52
    • Penicillin allergy: Lansoprazole 30mg + clarithromycin 500mg + metronidazole 500mg BD *10-14 days
  • Heartburn:
    • PO 15mg OD *2/52

Capsule: 30mg

Orodispersible tablet: 15mg

  • To be given before meals

Proton pump inhibitor

It binds to H+/K+-exchanging ATPase (proton pump) in gastric parietal cells, thereby causing suppression of basal and stimulated acid secretion

  • Headache
  • Diarrhea
  • Constipation
  • Vitamin B12 deficiency (long-term use)
  • Fundic gland polyps (long-term use)
  • Hypersensitivity to lansoprazole or other proton pump inhibitors
  • Co-administration with rilpivirine-containing products
  • Patients < 1 year
  • Erlotinib
  • Mavacamten
  • Nelfinavir
  • Rilpivirine

                          Drug Status

Availability Prescription or OTC
Pregnancy Category B; Can be used
Breastfeeding Can be used
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Degastrol 30mg Capsule 28’s Pharmaco Healthcare Pharmaco Healthcare
Lan 30mg Capsule 10’s Intas Pharma Accord Healthcare
Lanocid 30mg Capsule 10’s Harley’s Ltd Harley’s Ltd
Lanpro 30mg Capsule 50’s Unichem Labs Europa Healthcare
Lanzol 30mg Capsule 14’s Cipla Ltd Imperial Managed
Lanzol DT Junior 15mg Orodispersible tablet 120’s Cipla Ltd Imperial Managed
Lasoprol 30mg Capsule 14’s Delorbis Pharma Europa Healthcare
Lazope 30mg Capsule 10’s Metro Pharma Metro Pharma
Lazoton 30mg Capsule 30’s Cosmos Ltd Cosmos Ltd
Zapacid 30mg Capsule 30’s Win Medicare Europa Healthcare