• Acute migraine headache:
    • PO 25-100mg *1
    • Max: 200mg/day
  • Cluster headache:
    • SC 6mg (0.5 mL) with auto-injector
    • May repeat in ≥1 hour
    • Max 12mg/day
  • Tablet:
    • 100mg
    •  50mg

None remarkable

Selective 5-HT1 receptor agonist; Triptan

It activates vascular serotonin 5-HT1 receptors, producing vasoconstriction and anti-inflammatory effects

  • Injection site reaction (SC use)
  • Paresthesia
  • Hot sensation
  • Cold sensation
  • Malaise
  • Fatigue
  • Chest pain or discomfort
  • Neck pain or discomfort
  • Throat pain or discomfort
  • Jaw pain or discomfort
  • Dizziness
  • Vertigo
  • Flushing (SC use)
  • Weakness (SC use)
  • Sedation (SC use)
  • Drowsiness (SC use)
  • Diaphoresis (SC use)
  • Hypersensitivity to class/components
  • MAOI use within 14 days
  • Uncontrolled hypertension
  • Ischemic heart disease
  • Coronary vasospasm
  • Cardiac accessory conduction pathway disorder-associated arrhythmia
  • Cerebrovascular disease
  • Basilar/hemiplegic migraine
  • Peripheral Vascular Disease
  • Ischemic bowel disease
  • Severe hepatic impairment
  • Almotriptan
  • Bromocriptine
  • Cabergoline
  • Dihydroergotamine
  • Eletriptan
  • Ergotamine
  • Linezolid
  • Phenelzine
  • Frovatriptan
  • Methylergonovine
  • Naratriptan
  • Procarbazine
  • Rizatriptan
  • Yohimbe
  • Zolmitriptan

                          Drug Status

Availability Prescription only
Pregnancy Category C
Breastfeeding Avoid breastfeeding for 12 hours after therapy
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Imigran 100mg Tablet 6’s GSK Ltd GSK Ltd
Sumafix 50mg Tablet 20’s Aurobindo Pharma Simba Pharma
Sumafix 100mg Tablet 20’s Aurobindo Pharma Simba Pharma