• Hypertension:
    • 25mg/15mg OD.
    • Max 150mg captopril/50mg hydrochlorothiazide

Tablet: 50mg/25mg

  • Recommended to be taken 1 hour before meals
  • Less effective in African-Americans

Captopril: ACEIs

Hydrochlorothiazide: Thiazide diuretic

  • Rash
  • Pruritus
  • Taste changes
  • Hypotension
  • Dizziness
  • Fatigue
  • Cough
  • Hypokalemia
  • Hyperkalemia
  • Dyspepsia
  • Diarrhea
  • Elevated BUN/Cr
  • Myalgia
  • Hyperglycemia
  • Hyperuricemia
  • Photosensitivity
  • Proteinuria
  • Hypomagnesemia
  • Hypercalcemia
  • Hypophosphatemia
  • Hyponatremia
  • Sexual dysfunction
  • Weight loss
  • Hypersensitivity to drug/components
  • Hypersensitivity to sulfonamides
  • History of angioedema associated with ACEIs
  • Hereditary/ idiopathic angioedema
  • Pregnancy
  • Breastfeeding (HCTZ dose >50 mg/day)
  • Anuria
  • Severe renal impairment

WARNING:

Discontinue as soon as possible when pregnancy is detected

  • Aliskiren
  • Sacubitril/valsartan

                          Drug Status

Availability Prescription only
Pregnancy Category D
Breastfeeding Contraindicated
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Captopril+HCT Denk 50mg/25mg Tablet 100’s Denk Pharma Laborex Kenya