• Severe deficiency of water soluble vitamin B in alcohol abuse to prevent Wernicke’s Encephalopathy:
    • 2 to 3 pairs of 5 ml ampoules (1 pair = ampoule 1 + ampoule 2) diluted with 50ml-100ml infusion solution (normal saline/glucose 5%) and administered over 30 minutes every 8 hours. 
  • Psychiatric cases e.g. narcosis & toxicity from acute infections:
    • 1 pair of 5 ml ampoules diluted with 50ml-100ml infusion solution (normal saline or glucose 5%) administered over 30 minutes BD *1/52. 
  • Hemodialysis:
    • 1 pair of 5 ml ampoules diluted with 50 ml-100 ml infusion solution (normal saline or glucose 5%) administered over 30 minutes once every two weeks at the end of dialysis.

Each 5ml Ampoule No. 1:

  • Thiamine HCl 250mg
  • Pyridoxine HCl 50mg
  • Riboflavin 4mg

Each 5ml Ampoule No. 2:

  • Ascorbic acid 500mg
  • Nicotinamide 160mg
  • Glucose 1g

It can only be administered via an injection to the vein.

Vitamins B and C are important for a number of bodily functions including releasing energy from food and in the formation of healthy skin, bones and teeth.

Generally well tolerated.

  • Anaphylactic reactions
  • Low BP
  • Mild paraesthesia (pins & needles)
  • Mild pain at site of injection
  • Hypersensitivity to components

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                                   Drug Status

Availability Prescription only
Pregnancy Can be used
Breastfeeding Can be used
Schedule Not controlled
BRAND NAME FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Pabrinex Injection 6 pairs Kyowakirin Ltd Phillips Therapeutics