• Dissolution of gallstones:
    • Adult: 8–12 mg/kg OD nocte OR 2 divided doses for up to 2 years; treatment is continued for 3–4 months after stones dissolve.
  • Primary biliary cirrhosis:
    • Adult: 12–16 mg/kg daily in 3 divided doses for 3 months, then 12–16 mg/kg OD nocte

Tablet: 150mg, 300mg

To be taken at bedtime.

Diets with high cholesterol and calories should be avoided.

It reduces elevated liver enzyme levels by facilitating bile flow through the liver and protecting the liver cells. It also reduces the fractional reabsorption of cholesterol by the intestines. The reduced cholesterol saturation allows the gradual solubilization of cholesterol from gallstones, leading to their subsequent dissolution.

  • Diarrhoea
  • Pale stool
  • Headache
  • Dizziness
  • Dyspepsia
  • Nausea
  • Vomiting
  • Back pain
  • Upper RTI
  • Hypersensitivity reactions
  • Alopecia
  • UTI
  • Peptic ulcer
  • Flatulence
  • Acute gall bladder inflammation
  • Biliary colic
  • Non-functioning gall bladder
  • Radio-opaque stones
  • Known hepatocyte or bile ductal abnormalities
  • Inflammatory bowel disease
  • Biliary GI fistula
  • Patients requiring cholecystectomy
  • Antacids
  • Cyclosporine
  • Fibrates

                                   Drug Status

Availability Prescription only
Pregnancy Unknown; Not recommended
Breastfeeding Unknown; Not recommended
Schedule Not controlled
BRAND NAME STRENGTH FORMULATION PACK SIZE MANUFACTURER DISTRIBUTOR
Udihep 150mg Tablet 30’s Win Medicare Europa Healthcare
Udihep Forte 300mg Tablet 50’s Win Medicare Europa Healthcare
Ursoliv 250mg Capsule 50’s Mega Lifesciences Mega Lifesciences