- GERD
- Gastric and duodenal ulcers
10mg OD * 4-8 weeks
Tablet:
- 10mg
- Taken in the morning.
Proton Pump Inhibitor. R(+) enantiomer of racemate rabeprazole.
The PPI binds irreversibly to H+/K+ ATPase enzyme (proton pump) on gastric parietal cells and blocks the secretion of hydrogen ions, which combine with chloride ions in the stomach lumen to form gastric acid. PPIs block secretion of hydrogen ions into the stomach.
Generally well tolerated.
- Headache
- Diarrhoea
- Abdominal pain
- Flatulence
- Dry mouth
- Rash
- Hypersensitivity to drug
- Liver disease
- Kidney disease
- Ketoconazole
Drug Status
| Availability | Prescription or OTC by Pharmacist |
| Pregnancy | Unknown. Use only if clearly needed. |
| Breastfeeding | Unknown. Use only if clearly needed. |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Derbi | 10mg | Tablet | 10’s | Oriana Limited | Win-Pharma Ltd |
| Dexpure | 10mg | Tablet | 30’s | Emcure Pharma | Lazor Pharma |