- Uncomplicated UTI:
- Adult: 100mg BD *1/52
- Children >3 months: 3mg/kg in 4 divided doses*3-7 days
Tablets: 100mg
- Take with food or milk.
- Monitor closely for pulmonary function and withdrawn at first sign of pulmonary damage.
Nitrofuran antibiotic. It acts by altering bacterial ribosomal proteins and other macromolecules that interfere with metabolism and cell-wall synthesis.
- Nausea
- Vomiting
- Anorexia
- Abdominal pain
- Diarrhea
- Headache
- Drowsiness
- Vertigo
- Dizziness
- Nystagmus
- Intracranial hypertension
- Hypersensitivity reactions
- Acute pulmonary sensitivity reactions characterized by sudden onset fever, chills, eosinophilia, cough, chest pain, dyspnea, pulmonary infiltration and pleural effusion.
- Neonates <28 days old (can get hemolytic anemia)
- Renal disorders
- Pregnancy
- Lactation
- Labour & delivery
- Porphyria
- Hypersensitivity
- Elderly
- G6PD deficiency
- Oliguria
- Anuria
- Caution is taken in patients with:
- Anemia
- DM
- Electrolyte imbalance
- Pulmonary disease
- Vitamin Band folate deficiency
- Quinolone antibiotics
- Drugs that alkalinize urine
- Probenecid
- Sulfinpyrazone
- Antacids
Drug Status
| Availability | Prescription only |
| Pregnancy | Category B; Contraindicated |
| Breastfeeding | Contraindicated |
| Schedule | Not controlled |
| BRAND NAME | STRENGTH | FORMULATION | PACK SIZE | MANUFACTURER | DISTRIBUTOR |
|---|---|---|---|---|---|
| Nifuran | 100mg | Tablet | 100’s | Laboratory & Allied | Laboratory & Allied |
| Nitrofurantoin | 100mg | Tablet | 100’s | Cosmos Ltd | Cosmos Ltd |
| Nitrofurantoin | 100mg | Tablet | 100’s | Elys Chemicals | Elys Chemicals |