A parasitic infection caused by the protozoal organism Entamoeba histolytica.

Entamoeba histolytica.

Asymptomatic cases in cyst carriers.

Amoebic dysentery

  • Abdominal pains
  • Bloody/mucus diarrhea
  • Sometimes constipation
  • Constant urge to empty bowel
  • Fatigue

Amoebic liver abscess

  • Fever
  • Pain in r.hypochondrium referred to right shoulder.
  • Profuse sweating and rigor.
  • Palpable liver.
  • Tenderness & rigidity in r.hypochondrium
  • Bowel perforation
  • GI bleeding
  • Stricture formation
  • Intussusception
  • Peritonitis
  • Empyema
  • Stool microscopy for trophozites and cyst.
  • Liver U/S.
  • Needle aspiration for microscopy.
  • Chest X-ray.

Invasive intestinal amoebiasis:

–         Tabs/susp MTZ 800mg TDS *5/7.

ü 3-7 years: 200mg QID *5/7

ü 7-10years : 200-400mg TDS * 5/7

 

OR

–         Ornidazole 0.5-1gm daily *1-7 days.

 

OR

–         Satranidazole 300mg BD * 3-5 days.

 

OR

–         Tinidazole 2g daily *3/7.

Cyst carriers

–         FDC MTZ 250mg + diloxanide 250mg 1 tab TDS *5/7.

ü 5-12 years: ½ tab or 10mL * 5/7

ü < 5 years: 5mL TDS * 5/7

ü  

OR

–         Diloxanide 500mg BD *10/7

 

OR

–         Secnidazole 2g OD *3/7

ü Children: 30mg/kg OD *3/7

Amoebic liver abscess:

–         MTZ 30-50mg/kg/day in 3 divided doses for 7-10 days.

OR

–         Secnidazole 1.5g daily in one or several doses *5/7.

ü Childen: 30mg/kg/day in one or several doses *5/7

 

OR

–          Tinidazole 2g daily *3/7.